Clenbuterol is a β-2 adrenergic receptor agonist, acting on the sympathetic nervous system and is majorly used as a bronchodilator and a smooth muscle relaxant. It also acts on the B1 and B3 adrenoreceptors. Beyond treating breathing disorders, Clenbuterol is also commonly used as a thermogenic. It helps to loose excessive fat while still maintaining thin muscle mass and increase the metabolism (BMR), ultimately leading to more energy expenditure. It exerts many adrenaline-like flight and fight effects on the body.
Clenbuterol and fat loss
Clenbuterol helps during the cutting phase of the whole body-building procedure in which a person tries to offload loads of fat (majorly abdominal and visceral fat) which is retained during the preceding bulking phase where he has also accumulated muscle mass. It maintains the slim muscle mass. But there is a catch, Clenbuterol cannot make muscle lean on its own, it has to be supplemented with a caloric deficit of almost 50%, otherwise no fat loss will occur. But one thing must be kept in mind that muscle preservation action can only be retained with a proper diet plan. There is synchronization or management between this drug and a balanced régime, so you do not burn away muscle tissue.
Mechanism of Action
Clenbuterol is anabolic in nature. It induces fat burning through β-2 adrenergic receptor agonism activates the downstream signaling of β2-receptors, activate enzymes like lipase and perilipin, which mediates lipolysis (breakdown of lipids). Clenbuterol has been seen to highly affect the genetic signaling of adipocytes (fat cells). It raises the rate of fatty acid release from adipose tissue. It also acts through the process of breaking down triglycerides into fatty acids for oxidation and also leads to uncoupling, thus liberating enormous heat from the mitochondria.
The diet must include proteins and carbohydrates with minimum fat. There should be ever more fiber in the diet so that there is a sense of “fullness” which curbs the hunger and enhances thirst at the same time so that there is heavy water intake which helps in flushing the system. One of the major side effects of this drug is the loss of potassium ions from the body leading to dehydration, so one must drink more water. Periods of absolute fasting can prove to be serious.
So there must be a good balance between this drug and healthy abstaining in order to loose proper fat and no outright fasting. If the diet is off and the person is not serving his body with enough calories/protein then not even Clenbuterol will be able to stop the body from metabolizing muscle tissue for energy. So the main question arises why Clenbuterol if it can’t give any results on its own. The answer is that it simply augments the process of dieting by suppressing all the hunger cravings to control appetite, also maintain fat loss at more effective and efficient rate so you do not burn away muscle tissue and preserve it. Clen indirectly helps in burning fat by enhancing the process. There is no magic pill that will help anyone to lose weight and gain muscle absolutely effortlessly.